PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF KIGELIA PINNATA LINN LEAVES

  • Kalyani Kadam Department of Pharmacognosy, G.H. Raisoni Institute of life sciences, Nagpur, MH, India
  • Jayshree Patil Department of Pharmacology, G.H. Raisoni Institute of Life sciences Nagpur, MH, India
  • Dipti Kadam Department of Pharmacology, P.R. Pote college of Pharmacy, Amravati, MH, India
  • Chitrangana Ramteke Department of Pharmacognosy, Bajirao Karanjekar College of Pharmacy, Sakoli, MH, India
  • Jayshree Aate Department of Pharmacology, VIVA Institute of Pharmacy, Virar, MH, India
10.61280/tjpls.v12i1.179

Keywords:

Kigelia pinnata, Rutin, Powder microscopy, Moisture content, Extractive values, Sausage, Phytochemicals

Abstract

Kigelia pinnata Linn. belongs to the family of Bignoniaceae and commonly called the "Sausage" tree because of its hugs fruits. This species of tree can reach 20 meters in height. Sausage like appearance with long cord like stalks. It also known as Balam Kheera in Hindi. This plant is commonly found throughout in western and southern India and a few species in the Himalayas. It is a large evergreen glabrous tree measuring 8-10 m in height, stem, and trunk straight with branches in all direction. Bark is thick black. The leaves are opposite, compound, with 3-5 pairs of leaflets plus a terminal leaflets oblong up to 6-10 cm, roughly hairy on both surfaces.
In experimental work pharmacognostic and phytochemical parameters was find out such as physicochemical, preliminary-phytochemical and quantitative estimation of primary metabolites. The results of this experimental work shows that taxonomic characters, identification and to differentiate closely related species. And also, to find out active phytochemicals for further use.

Downloads

Download data is not yet available.

References

Meena, A. K., Bansal, P., & Kumar, S. (2009). Plants-herbal wealth as a potential

source of ayurvedic drugs. Asian Journal of Traditional Medicines, 4(4), 152-170.

Hemamalini, K., Vasireddy, U., & Bhargav, A. (2012). Studies on phyto chemical

profile and analgesic activity of methanolic leaf extract of Kigelia pinnata and Sophora

interrupta Bedd. International journal of Pharmaceutical Sciences, 4(2), 1856-70.

Dubey, N. K., Kumar, R., & Tripathi, P. (2004). Global promotion of herbal medicine:

India's opportunity. Current science, 86(1), 37-41.

Meena, A. K., Rao, M. M., Singh, A., & Kumari, S. (2010). Physicochemical and

preliminary phytochemical studies on the rhizome of Acorus calamus Linn. Indian J

Path Micro, 2, 130-131.

Stankovic, M. S. (2011). Total phenolic content, flavonoid concentration and

antioxidant activity of Marrubium peregrinum L. extracts. Kragujevac J Sci, 33(2011),

-72.

Msonthi, J. D., & Magombo, D. (1983). Medicinal herbs in Malawi and their

uses. Hamdard, 26(2), 94-100.

Hutchings, A. (1996). Zulu medicinal plants: An inventory. University of Natal press.

El-Sayyad, S. M. (1982). Flavonoids of the leaves and fruits of Kigelia

pinnata. Fitoterapia, 52, 189-191.

Khan, M. F., Dixit, P., Jaiswal, N., Tamrakar, A. K., Srivastava, A. K., & Maurya, R.

(2012). Chemical constituents of Kigelia pinnata twigs and their GLUT4 translocation

modulatory effect in skeletal muscle cells. Fitoterapia, 83(1), 125-129.

Bharti, N., Singh, S., Naqvi, F., & Azam, A. (2006). Isolation and in vitro antiamoebic

activity of iridoids isolated from Kigelia pinnata. Arkivoc, 10(10), 69-79.

Akunyili, D. N., Houghton, P. J., & Raman, A. (1991). Antimicrobial activities of the

stembark of Kigelia pinnata. Journal of Ethnopharmacology, 35(2), 173-177.

Moiden, S. V., Houghton, P. J., Croft, S. L., & Rock, P. (1998). Activity of Kigelia

pinnata root bark against Trypanosoma brucei trypomastigotes. Journal of Pharmacy

and Pharmacology, 50(SUPPL. 9), 224.

Weiss, C. R., Moideen, S. V., Croft, S. L., & Houghton, P. J. (2000). Activity of

extracts and isolated naphthoquinones from Kigelia pinnata against Plasmodium

falciparum. Journal of Natural Products, 63(9), 1306-1309.

Picerno, P. (2005). G, Marzocco S, Meloni M, Sanogo R, Aquino RP. Anti

inflammatory activity of verminoside from Kigelia africana and evaluation of

cutaneous irritation in cell cultures and reconstituted human epidermis. J Nat

Prod, 68(11), 1610-1614.

Silva, T. M. S., Da Silva, T. G., Martins, R. M., Maia, G. L. A., Cabral, A. G. S.,

Camara, C. A.& Barbosa-Filho, J. M. (2007). Molluscicidal activities of six species of

Bignoniaceae from north–eastern Brazil, as measured against Biomphalaria glabrata

under laboratory conditions. Annals of Tropical Medicine & Parasitology, 101(4),

-365.

Government College of Pharmacy, Amravati Page | 37 16. Tabanca, N., Pawar, R. S., Ferreira, D., Marais, J. P., Khan, S. I., Joshi, V., ... & Khan,

I. A. (2007). Flavan-3-ol-phenylpropanoid conjugates from Anemopaegma arvense

and their antioxidant activities. Planta medica, 73(10), 1107-1111.Hartmann, T.

(1999). Alkaloids: Biochemistry, Ecology, and Medicinal

Application. BioScience, 49(3), 238-240.

Jorge, M. P., Madjarof, C., Ruiz, A. L. T. G., Fernandes, A. T., Rodrigues, R. A. F., de

Oliveira Sousa, I. M., ... & de Carvalho, J. E. (2008). Evaluation of wound healing

properties of Arrabidaea chica Verlot extract. Journal of Ethnopharmacology, 118(3),

-366.

Leite, J.P., A.B. Oliveira, J.A. Lombardi, J.D. Filho and E. Chiari, 2006. Trypanocidal

activity of triterpenes from Arrabideae triplinervia and derivatives. Biological &

Pharmaceutical Bulletin, 29: 2307-2309

Kim, D. H., Han, K. M., Chung, I. S., Kim, D. K., Kim, S. H., Kwon, B. M., ... &

Baek, N. I. (2005). Triterpenoids from the flower of Campsis grandiflora K. Schum.

As human acyl-CoA: cholesterol acyltransferase inhibitors. Archives of pharmacal

research, 28(5), 550-556.

Dvorská, M., Žemlička, M., Muselík, J., Karafiátová, J., & Suchý, V. (2007).

Antioxidant activity of Catalpa bignonioides. Fitoterapia, 78(6), 437-439.

Park, B.M., S.S. Hong, C. Lee, M.S. Lee, S.J. Kang, Y.S. Shin, J.K. Jung, J.T. Hong,

Y. Kim, M.K. Lee and B.Y. Hwang, 2010. Naphthoquinones from Catalpa ovata and

their inhibitory effects on the production of nitric oxide. Archives of Pharmacal

Research, 33: 381-385.

Suzuki, R., Y. Yasui, H. Kohno, S. Miyamoto, M. Hosokawa, K. Miyashita and T.

Tanaka, 2006. Catalpa seed oil rich in 9t,11t,13c-conjugated linolenic acid suppresses

the development of colonic aberrant crypt foci induced by azoxymethane in rats.

Oncology Reports, 16: 989-996.

Fujiwara, A., T. Mori, A. Iida, S. Ueda, Y. Hano, T. Nomura, H. Tokuda and H.

Nishino, 1998. Antitumorpromoting naphthoquinones from Catalpa ovata. Journal of

Natural Products, 61: 629-632

Hetzel, C.E., A.A. Gunatilaka, T.E. Glass, D.G. Kingston, G. Hoffmann and R.K.

Johnson, 1993. Bioactive furanonaphthoquinones from Crescentia cujete. Journal of

Natural Products, 56: 1500-1505.

Rodrigues, A.M., J.E. de Paula, F. Roblot, A. Fournet and L.S. Espíndola, 2005.

Larvicidal activity of Cybistax antisyphilitica against Aedes aegypti larvae.

Fitoterapia, 76: 755-757

Joshi, A., & Roh, H. (2009). The role of context in work team diversity research: A

meta-analytic review. Academy of management journal, 52(3), 599-627.

Ferguson, N. M., & Lien, E. J. (1982). A flavonol neohesperidoside from Jacaranda

acutifolia. Journal of Natural Products, 45(5), 523-524.

Gachet, M.S. and W. Schühly, 2009. Jacaranda – An ethnopharmacological and

phytochemical review. Journal of Ethnopharmacology, 121: 14-27.

Di Stasi, L.C. and C.A. Hiruma-Lima, 2002. Plantas medicinais na Amazônia e na

Mata Atlântica. UNESP: Botucatu, 2 ed., São Paulo, pp. 451-452.

Botion, L.M., A.V. Ferreira, S.F. Côrtes, V.S. Lemos and F.C. Braga, 2005. Effects of

the Brazilian phytopharmaceutical product Ierobina on lipid metabolism and intestinal

tonus. Journal of Ethnopharmacology, 102: 137-142.

Gentry, A.H., 1992. Flora Neotropica: Monograph 25, Tribe Tecomeae, vol. 2. The

New York Botanical Garden, New York, pp 52-105.

Weniger, B., S. Robledo, G.J. Arango, E. Deharo, R. Aragón, V. Muñoz, J. Callapa, A.

Lobstein and R. Anton, 2001. Antiprotozoal activities of Colombian plants. Journal of

Ethnopharmacology, 78: 193-200.

Ogura, M., G.A. Cordell and N.R. Farnsworth, 1976. Potential anticancer agents. III.

Jacaranone, a novel phytoquinoid from Jacaranda caucana. Lloydia, 39: 255-257

Ogura, M., G.A. Cordell and N.R. Farnsworth, 1976. Potential anticancer agents. III.

Jacaranone, a novel phytoquinoid from Jacaranda caucana. Lloydia, 39: 255-257

Valadeau, C., A. Pabon, E. Deharo, J. Albán-Castillo, Y. Estevez, F.A. Lores, R.

Rojas, D. Gamboa, M. Sauvain, D. castillo and G. Bourdy, 2009. Medicinal plants

from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of

selected extracts. Journal of Ethnopharmacology, 123: 413-422

Ali, R.M., and P.J. Houghton, 1999. A new phenolic fatty acid ester with lipoxygenase

inhibitory activity from Jacaranda filicifolia. Planta Medica, 65: 455-457.

Ali, R.M., P.J. Houghton and T.S. Hoo, 1998. Antifungal activity of some

Bignoniaceae family found in Malaysia. Phytotherapy Research, 12: 331-334.

Prakash, L., and G. garg, 1980. Chemical examination of the root barks of Jacaranda

mimosaefolia D. Don and Tabebuia pentaphylla (Linn) Hemsl. Pharmazie, 35: 649.

Gachet, M.S. and W. Schühly, 2009. Jacaranda – An ethnopharmacological and

phytochemical review. Journal of Ethnopharmacology, 121: 14-27.

Sankara-Subramanian, S., S. Nagarajan and N. Sulochana, 1973. Hydroquinone from

the leaves of Jacaranda mimosaefolia. Phytochemistry, 12: 220-221.

Moharram, F.A., and M.S.A. Marzouk, 2007. A novel phenylethanoid dimer and

flavonoids from Jacaranda mimosaefolia. Zeitschrift für Naturforschung B, 62: 1213-

Binutu, O.A., K.E. Adesogan and J.I. Okogun, 1996. Antibacterial and antifungal

compounds from Kigelia pinnata. Planta Medica, 62: 352-353.

Duarte, D.S., M.F. Dolabela, C.E. Salas, D.S. Raslan, A.B. Oliveiras, A. Nenninger, B.

Wiedemann, H. Wagner, J. Lombardi and M.T. Lopes, 2000. Chemical

characterization and biological activity of Macfadyena unguis-cati (Bignoniaceae).

The Journal of Pharmacy and Pharmacology, 52: 347-352.

Tantangmo, F., B.N. Lenta, F.F. Boyom, S. Ngouela, M. Kaiser, E. Tsamo, B.

Weniger, P.J. Rosenthal and C. Vonthron-Sénécheau, 2010. Antiprotozoal activities of

some constituents of Markhamia tomentosa (Bignoniaceae). Annals of Tropical

Medicine and Parasitology, 104: 391-398.

Lima, C.S., E.L. De Amorim, S.C. Nascimento, C.F. Araújo, M.F. Agra, J.M.

Barbosa-Filho, M.S. Silva, E.V. Da-Cunha, I.J. Vieira and R. Braz-Filho, 2005.

Cytotoxic pyranonaphthoquinones from Melloa quadrivalvis (Bignoniaceae). Natural

Product Research, 19: 217-222.

Chulasiri, M., N. Bunyapraphatsara and P. Moongkarndi, 1992. Mutagenicity and

antimutagenicity of hispidulin and hortensin, the flavonoids from Millingtonia

hortensis L. Environmental and Molecular Mutagenesis, 20: 307-312.

Eyong, K.O., G.N. Folefoc, V. Kuete, V.P. Beng, K. Krohn, H. Hussain, A.E.

Nkengfack, M. Saeftel, S.R. Sarite and A. Hoerauf, 2006. Newbouldiaquinone A: A

naphthoquinone-anthraquinone ether coupled pigment, as a potential antimicrobial and

antimalarial agent from Newbouldia laevis. Phytochemistry, 67: 605-609.

Gafner, S., J.L. Wolfender, M. Nianga, H. Stoeckli-Evans and K. Hostettmann, 1996.

Antifungal and antibacterial naphthoquinones from Newbouldia laevis roots.

Phytochemistry, 42: 1315-1320.

Mbosso, E.J., S. Ngouela, J.C. Nguedia, V. Penlap, M. Rohmer and E. Tsamo, 2008.

Spathoside, a cerebroside and other antibacterial constituents of the stem bark of

Spathodea campanulata. Natural Product Research, 22: 296-304.

Borde, V., Sonwane, B., Sontakke, V., & Somwanshi, B. (2014). Isolation and

purification of alkaloids from medicinal plants by HPLC. International Journal of

Current Microbiology and Applied Sciences, 3(1), 414-423.

Zakaria, M., 1991. Isolation and characterization of active compounds from medicinal

plants. Asia Pac. J. Pharmacology. 6:pp15-20.

Dr.Sharda D.,Dr.Bhushan B.,Experimental Pharmacognosy and Phytochemistry ,Nirali

Prakashan

Govindachari, T. R., Patankar, S. J., & Viswanathan, N. (1971). Isolation and structure

of two new dihydroisocoumarins from Kigelia pinnata. Phytochemistry, 10(7), 1603-

Inoue, K., Inouye, H., & Chen, C. C. (1981). A naphthoquinone and a lignan from the

wood of Kigelia pinnata. Phytochemistry, 20(9), 2271-2276.

Chand, D., Dikshit, N., Shingane, S., & Gomashe, S. Kigelia pinnata DC. (Sausage

Tree)-A Medicinal Plant with great future perspectives.

Houghton, P. J., & Jâger, A. K. (2002). The sausage tree (Kigelia pinnata):

ethnobotany and recent scientific work. South African Journal of Botany, 68(1), 14-20.

Akunyili, D. N., & Houghton, P. J. (1993). Meroterpenoids and naphthaquinones from

Kigelia pinnata. Phytochemistry, 32(4), 1015-1018.

Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K. M., & Latha, L. Y. (2011).

Extraction, isolation and characterization of bioactive compounds from plants’

extracts. African Journal of Traditional, Complementary and Alternative

Medicines, 8(1).

Singh, A., Kumar, P., Kumar, A., Singh, R., & Tripathi, M. (2016). Pharmacognostical

studies on leaves of Kigelia pinnata Linn. Journal of Pharmacognosy and

Phytochemistry, 5(6), 93.

Binutu, O. A., Adesogan, K. E., & Okogun, J. I. (1996). Antibacterial and antifungal

compounds from Kigelia pinnata. Planta Medica, 62(04), 352-353.

Kumar, S., Kumar, V., & Prakash, O. M. (2012). Antidiabetic and hypolipidemic

activities of Kigelia pinnata flowers extract in streptozotocin induced diabetic

rats. Asian Pacific journal of tropical biomedicine, 2(7), 543-546.

Siddiqui, K., Mazumder, A., & Chakraborthy, G. (2015). A review on

phytopharmacological profile of Kigelia pinnata (Jacq.). International Journal of

Pharma Research & Review, 4(9), 34-8.

Saini, M., Sangwan, R., Khan, M. F., Kumar, A., Verma, R., & Jain, S. (2019).

Specioside (SS) & verminoside (VS) (Iridoid glycosides): isolation, characterization

and comparable quantum chemical studies using density functional theory

(DFT). Heliyon, 5(1), e01118.

Houghton, P. J., Photiou, A., Uddin, S., Shah, P., Browning, M., Jackson, S. J., &

Retsas, S. (1994). Activity of extracts of Kigelia pinnata against melanoma and renal

carcinoma cell lines. Planta medica, 60(05), 430-433.

Khan, M. F., Dixit, P., Jaiswal, N., Tamrakar, A. K., Srivastava, A. K., & Maurya, R.

(2012). Chemical constituents of Kigelia pinnata twigs and their GLUT4 translocation

modulatory effect in skeletal muscle cells. Fitoterapia, 83(1), 125-129.

Gouda, Y. G., Abdel-baky, A. M., Darwish, F. M., Mohamed, K. M., Kasai, R., &

Yamasaki, K. (2003). Iridoids from Kigelia pinnata DC. fruits. Phytochemistry, 63(8),

-892.

Jackson, S. J., Houghton, P. J., Retsas, S., & Photiou, A. (2000). In vitro cytotoxicity

of norviburtinal and isopinnatal from Kigelia pinnata against cancer cell lines. Planta

medica, 66(08), 758-761.

Joshi, K. C., Singh, P., Taneja, S., Cox, P. J., Howie, R. A., & Thomson, R. H. (1982).

New terpenoid aldehydes from Kigelia pinnata: crystal structure of

pinnatal. Tetrahedron, 38(17), 2703-2708.

Sharma, U. K., Singh, A., Sharma, U., Kumar, M., Rai, D., & Agrahari, P. (2010).

Wound healing activity of Kigelia pinnata bark extract. Asian Journal of

Pharmaceutical and Clinical Research, 3(4), 73-75.

Rahmatullah, M., Samarrai, W., Jahan, R., Rahman, S., Sharmin, N., Miajee, E. U., &

Azad, A. K. (2010). An ethnomedicinal, pharmacological and phytochemical review of

some Bignoniaceae family plants and a description of Bignoniaceae plants in folk

medicinal uses in Bangladesh. Advances in natural and applied sciences, 4(3), 236-

Statistics
114 Views | Downloads
Dimension Citations

Published

27-02-2025

How to Cite

Kalyani Kadam, Jayshree Patil, Dipti Kadam, Chitrangana Ramteke, and Jayshree Aate. “PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF KIGELIA PINNATA LINN LEAVES”. Tropical Journal of Pharmaceutical and Life Sciences, vol. 12, no. 1, Feb. 2025, pp. 45-65, doi:10.61280/tjpls.v12i1.179.

Issue

Section

Research Article