POLYMERIC NANO-CARRIERS FOR DRUG DELIVERY SYSTEMS IN CANCER THERAPY - AN EXHAUSTIVE REVIEW

J Pavan Kumar; Ranjan Kumar Singh; Chennu MM Prasada Rao; Rajeswari Tanniru; Ajay Garg

doi:10.61280/tjpls.v12i1.176

J Pavan Kumar Research Scholar, School of Pharmacy, Raffles University, Neemrana, Raj-301705.
Ranjan Kumar Singh Faculty School of Pharmacy, Raffles University, Neemrana, Raj-301705
Chennu MM Prasada Rao Faculty School of Pharmacy, Raffles University, Neemrana, Raj-301705
Rajeswari Tanniru Faculty School of Pharmacy, Raffles University, Neemrana, Raj-301705
Ajay Garg Faculty School of Pharmacy, Raffles University, Neemrana, Raj-301705

10.61280/tjpls.v12i1.176

Keywords:

Drug delivery systems, Nanoparticles, Nanocarriers, Tumor, Chemotherapy, Pharmacokinetics

Abstract

Progress in molecular pharmacology and a better comprehension of the mechanism of various diseases have necessitated the precise targeting of the cells responsible for initiating and advancing these diseases. This is particularly applicable to the majority of life-threatening illnesses that necessitate treatment medicines with multiple adverse effects. Therefore, precise tissue targeting is necessary to minimize systemic exposure. Modern drug delivery systems (DDS) are developed utilizing cutting-edge technology to expedite the administration of drugs across the body to a particular target area, optimizing the effectiveness of the treatment and reducing the buildup of drugs in unintended areas of the body. Consequently, they significantly impact the management and treatment of diseases. Modern drug delivery systems (DDS) provide significant advantages over traditional methods. These include improved performance, automation, precision, and efficacy. They consist of nanomaterials or miniaturized devices that comprise multifunctional components. These components are biocompatible, biodegradable, and possess high viscoelasticity, resulting in a longer circulating half-life. This article thoroughly examines the history and technological progress of medication delivery systems. The text provides an update on the latest advancements in drug delivery systems, including their therapeutic applications used in Cancer, their present obstacles, and potential future improvements for enhanced performance and utilization.

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